The Enlightened Economy: An Economic History of Britain, 1700-1850. It is certainly the most comprehensive treatment of the subject I have ever read. I learned something on every page.
I hesitate to recommend Mokyr's book to a general (i.e., nonacademic) readership only because of its academic/analytical tone. This is not a popular history book of the Barbara Tuchman or David McCullough variety. That said, Mokyr writes with sufficient clarity that I think nonacademic readers could get a lot out of the book.